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"A large, well-designed clinical trial called START has confirmed that by initiating anti-HIV therapy early -- when their CD4+ cell counts are still relatively high -- HIV-positive people can significantly reduce their risk of developing AIDS, other serious illnesses unrelated to AIDS or dying. According to the U.S. National Institute of Allergy and Infectious Diseases (NIAID), the results from START 'support offering treatment to everyone with HIV.'"
THIS HAS BEEN PROOVED BY From CATIE (June 1, 2015): Study Confirms Starting HIV Treatment Early Prevents Illness and Death,Beside this,other two research studies in the field about the risk of transmission -- HPTN 052 and PARTNER -- and now we have START, dealing with the benefits of very early HIV treatment. Now the first two have sometimes been called "game-changers". it's a tremendous advance in knowledge,It's going to affect things forever in that this will be the trial that settles any prior scientific uncertainty about the importance of starting HIV therapy as soon as possible after diagnosis. This will be remembered just like the landmark studies as mentioned. The early release of data from START will one day be seen as a very important event in the history of the HIV pandemic.
But there are sub-studies within START that are looking at brain health, bone health, heart health and so on and they are probably going to reveal, as some other studies have, that starting treatment early protects and preserves vital organs from further deterioration. It's going to be really big and will add further momentum to the message of starting treatment as early as possible.
And this will have important applications for all sorts of people, right? Newly diagnosed of course, but doctors and, people who work in AIDS Service Organizations,on the whole range of people and agencies involved in the health and education around HIV,nurses, clinics, pharmacists and of course, community-based organizations.
CATIE has been saying for some time that there has been mounting evidence from studies that starting treatment early results in substantial benefits. And of course some community advocates have been suggesting way before this announcement that early treatment is the way to go, even without this gold standard evidence.There are always people who are cautious and it was reasonable to have such caution in the past few years until the release of the START results. Few people expected the size of the difference in outcomes to be so large between the two groups -- those who started treatment early and those who didn't.
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