DEAD HEART MUSCLE TO BE REPLACED BY HEART PATCH AFTER HEART ATTACK

DEAD HEART MUSCLE TO BE REPLACED BY HEART PATCH AFTER HEART ATTACK

Prof Dr,DRAM,HIV /AIDS,HEPATITIS ,SEX DISEASES & WEAKNESS expert,New Delhi,India, +917838059592

Heart attack or Myocardial Infarction lead to death of few cardiac muscle and these are never repaired by any medicine till today.As a result if severe death either cardiac failure and death or if in time managed replaced naturally by weak scar patch which canot contract or pass electrical signals of Heart .The end result is a disease commonly referred to as heart failure that affects over 12 million patients worldwide.

       Now a heart patch has been developed developed by biomedical engineers at Duke University in the US from pluripotent cells in human being and  has been tried in mouse and is successful. For heart patches to work, it must be large enough to cover the affected tissue. It must also be just as strong and electrically active as the native heart tissue, or else the discrepancy could cause improper beating of the heart."Creating individual cardiac muscle cells is pretty commonplace, but people have been focused on growing miniature tissues for drug development," Nenad Bursac, Professor of Biomedical Engineering at Duke, said.

               Tests showed that the heart muscle in the patch was fully functional, with electrical, mechanical and structural properties that resemble those of a normal, healthy adult heart."This is extremely difficult to do, as the larger the tissue that is grown, the harder it is to maintain the same properties throughout it," said Bursac. "Equally challenging has been making the tissues mature to adult strength on a fast timescale of five weeks while achieving properties that typically take years of normal human development," Bursac added. 

           The researchers showed that these cardiac patches survive, become vascularised and maintain their function when implanted onto mouse and rat hearts. For a heart patch to ever actually replace the work of dead cardiac muscle in human patients, however, it would need to be much thicker than the tissue grown in this study. The researchers said they were working on making it possible.